Anti-CD63 antibody (Ab68418)
CD63, MLA1, TSPAN30, CD63 antigen, Granulophysin, Lysosomal-associated membrane protein 3, Lysosome integral membrane protein 1, Melanoma-associated antigen ME491, OMA81H, Ocular melanoma-associated antigen, Tetraspanin-30, LAMP-3, Limp1, Tspan-30
详细信息
背景信息
Product Specifications Anti-CD63 antibody (ab68418) is a rabbit polyclonal antibody and is validated for use in WB in human samples. Anti-CD63 antibody (ab68418) specifically detects CD63 (UniProt ID: P08962; Molecular weight: 26kDa) and is sold in 100 µg selling sizes. Quality and Validation Abcam's high quality validation processes ensure Anti-CD63 antibody (ab68418) has high sensitivity and specificity. The specificity of Anti-CD63 antibody (ab68418) has been confirmed by testing in knockout samples. Anti-CD63 antibody (ab68418) has been cited over 123 times in peer reviewed journals and is trusted by the scientific community. Target Information CD63, also known as LAMP3 or Granulophysin, is a member of the tetraspanin family and is widely expressed on the surface of various cells, including macrophages and lymphocytes. It plays a crucial role in the formation and release of exosomes. CD63 (Granulophysin) is highly expressed in various tumor cells and also impacts the tumor microenvironment (TME) by regulating cell communication. Additionally, CD63 facilitates the degradation of the extracellular matrix, aiding in tumor cell invasion and metastasis.
文献引用 (178)
Magnetic-Assisted Aptamer Selection and Isolation of Migrasomes for Application in Lung Adenocarcinoma Proteomic Analysis.
磁辅助适体筛选和迁移体分离及其在肺腺癌蛋白质组学分析中的应用。
BMSC-derived exosomes facilitate osteogenesis and ameliorate ageing-related bone loss through restoring Th17/Treg homeostasis via the miR-21/Skp2/FoxO1 axis.
BMSC 衍生的外泌体通过 miR-21/Skp2/FoxO1 轴恢复 Th17/Treg 稳态，促进成骨作用并改善与衰老相关的骨质流失。
Mesenchymal Stem Cell-Derived Extracellular Vesicles Attenuate Pro-Inflammatory Macrophage Polarization: Comparison of Matrix-Bound and Small Extracellular Vesicles.
间充质干细胞衍生的细胞外囊泡减弱促炎巨噬细胞极化：基质结合型和小细胞外囊泡的比较。
Exosomal microRNA-448 suppresses the malignant behaviors of liver cancer cells by targeting RAB7A and inhibiting glycolysis.
外泌体microRNA-448通过靶向RAB7A和抑制糖酵解来抑制肝癌细胞的恶性行为。
Integrated multi-omics profiling of plasma extracellular vesicles reveals the hsa-miR-1-3p-LRP1 axis as a potential biomarker in cervical cancer.
对血浆细胞外囊泡进行多组学综合分析，揭示了 hsa-miR-1-3p-LRP1 轴是宫颈癌的潜在生物标志物。
Dual-mode action of scalable, high-quality engineered stem cell-derived SIRPα-extracellular vesicles for treating acute liver failure
利用可扩展的高质量工程化干细胞衍生SIRPα-细胞外囊泡的双重作用机制治疗急性肝衰竭
RDYH58 functional exosomes targeting myofibroblasts loaded with siFKBP10 for inhibition of collagen biosynthesis and secretion of IPF.
RDYH58 功能性外泌体靶向肌成纤维细胞，负载 siFKBP10 以抑制 IPF 的胶原蛋白生物合成和分泌。
AZIN1 level is increased in medulloblastoma and correlates with c-Myc activity and tumor phenotype
AZIN1 水平在髓母细胞瘤中升高，并与 c-Myc 活性和肿瘤表型相关
RNA Sequencing at Single Vesicle Resolution via 3D Printed Embedded Droplet Arrays.
利用 3D 打印嵌入式液滴阵列实现单囊泡分辨率的 RNA 测序。
Chronic Obstructive Pulmonary Disease Airway Epithelial Cell-derived Extracellular Vesicles Spread Cellular Senescence via MicroRNA-34a.
慢性阻塞性肺疾病气道上皮细胞衍生的细胞外囊泡通过MicroRNA-34a传播细胞衰老
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