用户验证的应用
经验证应用
| 项目 | 详情 |
|---|---|
| Positive WB detected in | rat stomach tissue, rabbit stomach tissue, pig vein tissue, pig stomach tissue, rabbit large intestine tissue, pig colon tissue, rat colon tissue, mouse colon tissue |
| Positive IHC detected in | human colon tissue, human appendicitis tissue, human liver tissue, human liver cancer tissue, rat colon tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Positive IF-P detected in | rat heart tissue |
| Positive IF-Fro detected in | mouse breast cancer |
| Positive IF/ICC detected in | C2C12 cells |
| Positive FC (Intra) detected in | C2C12 cells |
推荐稀释说明
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. Sample-dependent, Check data in validation data gallery.
详细信息
背景信息
ACTA2 (also known as α-smooth muscle actin or α-SMA) belongs to the actin family. Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. ACTA2 is primarily expressed in vascular smooth muscle and anti-ACTA2 is commonly used to marker smooth muscle cells.
文献引用 (76)
Fibrotic scar formation after cerebral ischemic stroke: Targeting the Sonic hedgehog signaling pathway for scar reduction.
脑缺血性中风后纤维化瘢痕形成：靶向 Sonic hedgehog 信号通路以减少瘢痕
Cytoplasmic and nuclear NFATc3 cooperatively contributes to vascular smooth muscle cell dysfunction and drives aortic aneurysm and dissection.
细胞质和细胞核中的 NFATc3 协同作用，导致血管平滑肌细胞功能障碍，并引发主动脉瘤和主动脉夹层
CCN2 mediates fibroblast-macrophage interaction in knee arthrofibrosis based on single-cell RNA-seq analysis
基于单细胞 RNA 测序分析，CCN2 介导膝关节纤维化中的成纤维细胞-巨噬细胞相互作用
GLSP mitigates vascular aging by promoting Sirt7-mediated Keap1 deacetylation and Keap1-Nrf2 dissociation
GLSP通过促进Sirt7介导的Keap1去乙酰化和Keap1-Nrf2解离来缓解血管老化。
Targeting PIM1 by Bruceine D attenuates skin fibrosis via myofibroblast ferroptosis
布鲁辛D靶向PIM1可通过诱导肌成纤维细胞铁死亡来减轻皮肤纤维化。
Human adipose-derived mesenchymal stem cell-derived exosomes induce epithelial remodeling and anti-scar healing revealed by single-cell RNA sequencing
单细胞RNA测序揭示，人脂肪间充质干细胞来源的外泌体可诱导上皮重塑和抗瘢痕愈合。
Elastin-like polypeptide and triclosan-modified PCL membrane provides aseptic protection in tissue regeneration.
弹性蛋白样多肽和三氯生修饰的PCL膜在组织再生中提供无菌保护
Synergistic exacerbation of periprosthetic osteolysis by inflammatory bowel disease and titanium ions: Impaired osteogenesis of BMSCs via PI3K/AKT signaling.
炎症性肠病和钛离子协同加剧假体周围骨溶解：通过 PI3K/AKT 信号通路损害 BMSC 的成骨作用
Self-assembled extracellular matrix-lipid nanoparticle composite for site-specific siRNA delivery to improve cardiac repair post-myocardial infarction.
自组装细胞外基质-脂质纳米颗粒复合材料用于定点siRNA递送，以改善心肌梗死后的心脏修复
Inhibition of Rho GEFs attenuates pulmonary fibrosis through suppressing myofibroblast activation and reprogramming profibrotic macrophages.
抑制 Rho GEF 可通过抑制肌成纤维细胞活化和重编程促纤维化巨噬细胞来减轻肺纤维化
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