Anti-MAP2 antibody [HM-2] - Neuronal Marker (Ab11267)

Mtap2, Map2, Microtubule-associated protein 2, MAP-2

反应种属:Rat
抗原名称:MAP2
应用:WB, IF/ICC

用户验证的应用

推荐稀释比例

  • WB1-2 µg/mL
  • ICC2 µg/mL Fix cells in 4% paraformaldehyde/PBS for 45 min; then permeabilise cells with 0.2% Triton X-100 in PBS for 5 min (see Farah et al) OR fix in 4% paraformaldehyde (containing 0.2% picric acid in 0.1 M phosphate buffer, pH 6.9) for 15 min at room temperature (see O' Hare et al).

详细信息

免疫原Full Length Protein corresponding to Rat Map2. The exact immunogen used to generate this antibody is proprietary information. P15146
宿主/亚型Mouse / IgG1
抗体类型Monoclonal
全称Anti-MAP2 antibody [HM-2] - Neuronal Marker
产品形式Liquid
储存缓冲液pH: 7.4 Preservative: 0.097% Sodium azide Constituents: PBS
储存条件运输条件: Blue Ice 推荐的短期储存条件: +4°C 推荐的长期储存条件: -20°C 储存信息: Avoid freeze / thaw cycle

背景信息

What is this antibody validated in? Anti-MAP2 antibody [HM-2] (ab11267) is a mouse monoclonal antibody and is validated for use in Western Blot (WB) in Rat samples. What is the molecular weight of MAP2? Anti-MAP2 [HM-2] (ab11267) specifically detects a band for MAP2 (UniProt: P11137) at a molecular weight of 200kDa. Trusted by the scientific community Anti-MAP2 [HM-2] (ab11267) was first used in a scientific publication in 2004 and has been cited over 170 times in peer-reviewed journals. Reviewed by scientists Anti-MAP2 [HM-2] (ab11267) has over 5 independent reviews from customers.

文献引用 (176)

Temporal regulation of human reactive astrocytes reveals their capacity for antigen presentation.

人类反应性星形胶质细胞的时间调控揭示了它们呈递抗原的能力。

Hill Emily Jane, Sojka Caitlin, Sampson Maureen McGuirk, Kebede Nardos, Wang Hsiao-Lin V, Showrin Shainoor, King Alexia Tyler, Sing Anson David, Chang Jianjun, Faundez Victor, Sampson Timothy R, Venneti Sriram, Sloan Steven A

Ubiquitin ligase Nedd4 regulates the abundance and toxicity of mutant huntingtin.

泛素连接酶 Nedd4 调节突变亨廷顿蛋白的丰度和毒性。

Jeong Hyunkyung, Qin Yiyang, Xu Fangke, Trajkovic Katarina, Kim Myung Jong, Marotta Nicolas, Hamada Kana, Allada Ravi, Yang Su, Krainc Dimitri

KCNB1 mutation impairs neuronal differentiation by disrupting gene expression temporal regulation and neuron-specific pathways.

KCNB1 突变会破坏基因表达的时间调控和神经元特异性通路,从而损害神经元分化。

Guo Yufan, Wu Lifang, Ye Danfeng, Lin Xueting, Jin Yuting, Zhang Chudi, Lou Yuting, Miao Pu, Wang Ye, Zhang Bijun, Feng Jianhua

Gastrodin alleviates neuronal damage in epileptic cell models by targeting P2RY12 to inhibit microglial hyperactivation.

天麻素通过靶向 P2RY12 抑制小胶质细胞过度激活,从而减轻癫痫细胞模型中的神经元损伤。

Cai Aiyuan, Li Zilong, Liu Ran, Huang Hailong, Liu Ping, Zhang Ruizhong, Xiao Jing, Lin Yuanhong, Hu Qingpeng, Wu Haixia

Genetically Programmed Single-Component Protein Hydrogel for Spinal Cord Injury Repair.

用于脊髓损伤修复的基因编程单组分蛋白水凝胶

Wei Yi, Zhou Xiaolin, Li Zhenhua, Liu Qing, Ding Han, Zhou Yunlong, Yin Ruo-Feng, Zheng Lifei

p-Coumaric acid alleviates neuronal damage in ischemic stroke mice by promoting BACH1 nuclear export and degradation.

对香豆酸通过促进 BACH1 核输出和降解来减轻缺血性中风小鼠的神经元损伤

Song Meng-Lu, Sun Yun-Yun, Yin Hai-Jun, Li Yi, Yang Hua

In utero rescue of neurological dysfunction in a mouse model of Wiedemann-Steiner syndrome

在维德曼-施泰纳综合征小鼠模型中,通过子宫内干预挽救神经功能障碍

Tinna Reynisdottir ,Kimberley J Anderson ,Katrin Möller ,Stefán Pétursson ,Andrew Brinn ,Katheryn P Franklin ,Juan Ouyang ,Asbjorg O Snorradottir ,Cathleen M Lutz ,Aamir R Zuberi ,Valerie B DeLeon ,Hans T Bjornsson

Reduced mesencephalic astrocyte-derived neurotrophic factor expression by mutant androgen receptor contributes to neurodegeneration in a model of spinal and bulbar muscular atrophy pathology

突变雄激素受体导致中脑星形胶质细胞衍生神经营养因子表达减少,从而促进脊髓延髓肌萎缩症病理模型中的神经退行性变。

Yiyang Qin,Wenzhen Zhu, Tingting Guo, Yiran Zhang, Tingting Xing, Peng Yin, Shihua Li, Xiao-Jiang Li, Su Yang

Prion replication in organotypic brain slice cultures is distinct from in vivo inoculation and is species dependent.

朊病毒在器官型脑片培养物中的复制与体内接种不同,并且具有物种依赖性

Slota Jessy A, Lamoureux Lise, Myskiw Jennifer, Frost Kathy L, Medina Sarah J, Kielich Dominic M S, Leonhardt Melanie, Thapar Gunjan, Bailey-Elkin Ben A, Booth Stephanie A

Cathepsin B deficiency disrupts cortical development via PEG3, leading to depression-like behavior.

组织蛋白酶 B 缺乏通过 PEG3 破坏皮层发育,导致类似抑郁的行为

Xie Zhen, Yang Qinghu, Lan Fei, Kong Wei, Zhao Shuxuan, Sun Jinyi, Yan Yan, Quan Zhenzhen, Bai Zhantao, Qing Hong, Mao Jian, Ni Junjun
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