Anti-CD44 antibody (Ab157107)
CD44, LHR, MDU2, MDU3, MIC4, CD44 antigen, CDw44, Epican, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, Phagocytic glycoprotein 1, Phagocytic glycoprotein I, ECMR-III, PGP-1, PGP-I
详细信息
背景信息
Product Specifications Anti-CD44 antibody (ab157107) is a rabbit polyclonal antibody and is validated for use in IHC-P, IP, WB in human, mouse, rat samples. Anti-CD44 antibody (ab157107) specifically detects CD44 (UniProt ID: P16070; Molecular weight: 79kDa) and is sold in 100 µL selling sizes. Quality and Validation Abcam's high quality validation processes ensure Anti-CD44 antibody (ab157107) has high sensitivity and specificity. Anti-CD44 antibody (ab157107) has been cited over 188 times in peer reviewed journals and is trusted by the scientific community. Anti-CD44 antibody (ab157107) has 31 independent reviews from customers. Target Information CD44 is a cell-surface glycoprotein involved in various physiological functions such as cell proliferation, adhesion, migration, and lymphocyte activation. It plays a significant role in the pathology of diseases like cancer, arthritis, and infections by interacting with its principal ligand, hyaluronic acid. CD44 plays a significant role in autoimmune diseases by mediating inflammatory responses and immune cell interactions. It is involved in the activation and migration of lymphocytes, which are crucial in the development of autoimmune conditions. For instance, targeting CD44 with monoclonal antibodies has shown anti-inflammatory effects in murine models of autoimmune diseases like arthritis and experimental autoimmune encephalomyelitis (EAE)
文献引用 (223)
Hyaluronan regulates the assembly structure and biofunction of polycationic silk fibroin to boost microfracture.
透明质酸调节聚阳离子丝素蛋白的组装结构和生物功能，从而促进微裂纹形成。
Mannose Oligosaccharide-Conjugated In Situ Pore-Forming Injectable Hydrogels for Rheumatoid Arthritis Treatment by Reprogramming Macrophage Extracellular Vesicles
通过重编程巨噬细胞外囊泡，制备用于治疗类风湿性关节炎的甘露糖寡糖偶联原位成孔注射水凝胶
Cuproptosis-inducing photothermal nanotherapy coupled with ECM destabilization drives potent tumor regression and immune reawakening.
诱导铜凋亡的光热纳米疗法与细胞外基质不稳定化相结合，可有效促进肿瘤消退和免疫复苏。
Repurposing statins and phenothiazines to treat chemoresistant neuroblastoma.
利用他汀类药物和吩噻嗪类药物治疗化疗耐药性神经母细胞瘤。
Chimeric antigen receptor T cell targeting CD44E variant in HCC holds therapeutic potential.
嵌合抗原受体T细胞靶向肝细胞癌中的CD44E变体具有治疗潜力。
Glioblastoma Cells Expressing Oncogenic EGFR Release Multiple Extracellular Vesicle Subpopulations Positive or Negative for EGFR.
表达致癌性 EGFR 的胶质母细胞瘤细胞释放多种 EGFR 阳性或阴性的细胞外囊泡亚群。
Alpha-enolase influences ATP pool of cytoplasm and lactate homeostasis by regulating glycolysis in gastric cancer.
α-烯醇化酶通过调节胃癌中的糖酵解来影响细胞质中的ATP池和乳酸稳态。
Bio-barrier-adaptable biomimetic nanomedicines combined with ultrasound for enhanced cancer therapy.
生物屏障适应性仿生纳米药物与超声波结合，可增强癌症治疗效果
A novel CD44-targeting aptamer recognizes chemoresistant mesenchymal stem-like TNBC cells and inhibits tumor growth.
一种新型的 CD44 靶向适体可识别耐药的间充质干细胞样 TNBC 细胞并抑制肿瘤生长
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