Curcumin protects intestinal mucosal barrier function of rat enteritis via activation of MKP-1 and attenuation of p38 and NF-κB activation

姜黄素通过激活MKP-1、减弱p38和NF-κB活化来保护大鼠肠炎肠黏膜屏障功能

阅读:6
作者:Wei-Bing Song, Yuan-Yuan Wang, Fan-Su Meng, Qing-Hua Zhang, Jian-Ying Zeng, Li-Ping Xiao, Xin-Pei Yu, Dan-dan Peng, Lei Su, Bing Xiao, Zhen-Shu Zhang

Background

Intestinal mucosa barrier (IMB) dysfunction

Significance

The effect of curcumin is mediated by the MKP-1-dependent inactivation of p38 and inhibition of NF-κB-mediated transcription. Curcumin, with anti-inflammatory and anti-oxidant activities may be used as an effective reagent for protecting intestinal mucosa barrier and other related intestinal diseases.

特别声明

1、本页面内容包含部分的内容是基于公开信息的合理引用;引用内容仅为补充信息,不代表本站立场。

2、若认为本页面引用内容涉及侵权,请及时与本站联系,我们将第一时间处理。

3、其他媒体/个人如需使用本页面原创内容,需注明“来源:[生知库]”并获得授权;使用引用内容的,需自行联系原作者获得许可。

4、投稿及合作请联系:info@biocloudy.com。