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【文献解析】小鼠出生后发育过程中谷氨酸/GABA双递质神经元的全脑时空图谱绘制

1. 领域背景与文献文献英文标题:Brain-wide spatiotemporal mapping of glutamate/GABA dual-transmitter neurons during postnatal development in mice;发表期刊:Cell Biosci;影响因子:未公开;研究领域:神经科学(神经元递质调控与发育生物学)传统神经科学领域长期遵循“戴尔原则”,认为单个神经元仅合成并释放一

【文献解析】Correction: Overcoming acquired resistance to cetuximab by dual targeting HER family receptors with antibody-based therapy

1. 领域背景与文献文献英文标题:Correction: Overcoming acquired resistance to cetuximab by dual targeting HER family receptors with antibody-based therapy;发表期刊:Mol Cancer;影响因子:未公开;研究领域:肿瘤学(靶向治疗耐药机制)西妥昔单抗(Cetuximab)是针对表皮生长因子受体(EGFR)的人鼠嵌合单克隆

【文献解析】Fibroblast growth factor receptor substrate 2 interactome mapping reveals novel candidate interactors associated with migration and invasion

1. 领域背景与文献文献英文标题:Fibroblast growth factor receptor substrate 2 interactome mapping reveals novel candidate interactors associated with migration and invasion;发表期刊:Cell Communication and Signaling;影响因子:5.9(2025年);研究领域:儿童分子神经肿瘤学(髓母细胞瘤方向)成纤维细胞生

【文献解析】α-突触核蛋白的性别依赖性神经元效应揭示GABA能传递对睡眠调控神经元的神经保护作用

1. 领域背景与文献引入文献英文标题:Sex-dependent neuronal effects of α-synuclein reveal that GABAergic transmission is neuroprotective of sleep-controlling neurons;发表期刊:Cell Bioscience;影响因子:未公开;研究领域:神经科学(帕金森病与睡眠障碍)帕金森病(PD)是全球范围内最常见的神经退行性疾病之

Degradation of the LDL receptors by PCSK9 is not mediated by a secreted protein acted upon by PCSK9

1. 领域背景与文献引入文献英文标题:Degradation of the LDL receptors by PCSK9 is not mediated by a secreted protein acted upon by PCSK9 extracellularly;发表期刊:BMC Cell Biology;影响因子:未公开;研究领域:脂蛋白代谢与细胞生物学(PCSK9调控低密度脂蛋白受体机制)领域共识:胆固醇稳态调控是心血管疾病研

Simultaneous stimulation of GABA and beta adrenergic receptors stabilizes isotypes of activated aden

1. 领域背景与文献引入文献英文标题:Simultaneous stimulation of GABA and beta adrenergic receptors stabilizes isotypes of activated adenylyl cyclase heterocomplex;发表期刊:BMC Cell Biology;影响因子:未公开;研究领域:神经信号转导(G蛋白偶联受体调控腺苷酸环化酶的机制研究)G蛋白偶联受体(GPCR)是细胞

Polymorphisms of Toll-like receptor-4 and CD14 in systemic lupus erythematosus and rheumatoid arthri

1. 领域背景与文献引入文献英文标题:Polymorphisms of Toll-like receptor-4 and CD14 in systemic lupus erythematosus and rheumatoid arthritis;发表期刊:Biomark Res;影响因子:未公开;研究领域:自身免疫病(系统性红斑狼疮、类风湿关节炎)与Toll样受体4(TLR4)、CD14基因多态性关联研究。 Toll样受体4(TLR4)

Glucagon-like peptide 1 receptor agonists and cancer risk: advancing precision medicine through mech

1. 领域背景与文献引入文献英文标题:Glucagon-like peptide 1 receptor agonists and cancer risk: advancing precision medicine through mechanistic understanding and clinical evidence;发表期刊:Biomarker Research;影响因子:未公开;研究领域:糖尿病治疗与癌症风险(细分领域:GLP-1受体激动剂的肿瘤学效应)。

【文献解析】Targeting toll-like receptor 7/8 for immunotherapy: recent advances and prospectives

1. 领域背景与文献引入文献英文标题:Targeting toll-like receptor 7/8 for immunotherapy: recent advances and prospectives;发表期刊:Biomarker Research;影响因子:未公开;研究领域:肿瘤免疫治疗(Toll样受体7/8靶向策略)。 Toll样受体(TLR)是固有免疫系统的核心模式识别受体,通过识别病原体相关分子模式(P